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Sunday, May 24, 2009

MRI guided radiation therapy (MRIgRT)


At the UMC Utrecht, The Netherlands, we have constructed a prototype MRI
accelerator. The prototype is amodified 6MVElekta (Crawley, UK) accelerator
next to a modified 1.5 T Philips Achieva (Best, The Netherlands) MRI system.
From the initial design onwards, modifications to both systems were aimed to
yield simultaneous and unhampered operation of the MRI and the accelerator.
Indeed, the simultaneous operation is shown by performing diagnostic quality
1.5 T MRI with the radiation beam on. No degradation of the performance of
either system was found. The integrated 1.5 T MRI system and radiotherapy
accelerator allowsimultaneous irradiation andMRimaging. The full diagnostic
imaging capacities of the MRI can be used; dedicated sequences for MRIguided
radiotherapy treatments will be developed. This proof of concept opens
the door towards a clinical prototype to start testing MRI-guided radiation
therapy (MRIgRT) in the clinic.


The integrated 1.5 T MRI system and radiotherapy accelerator allow simultaneous irradiation
and MR imaging. Both systems operate independently. The full diagnostic imaging capacities
of the Philips MRI can be used; dedicated sequences for guiding radiotherapy treatments will
be developed.
This proof of concept opens the door towards a clinical prototype to start testing MRIguided
radiation therapy (MRIgRT) in the clinic.

Acknowledgments
This research is supported by the Technology Foundation STW (applied science division of
NWO and the technology programme of the Ministry of Economic Affairs) and by the Dutch


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