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Monday, March 03, 2014

Twin brains afflicted with Alzheimer's show similar patterns of neuropathologic changes

 Posted by

Robert Karl Stonjek





In a unique study, an international team of researchers led by USC
Dornsife psychologist Margaret Gatz compared the brains of twins where
one or both died of Alzheimer's disease. They found that many of the
twin pairs not only had similar progressions of Alzheimer's disease and
dementia prior to death, but they also had similar combinations of
pathologies-two or more unconnected areas of damage to the brain.



"Identical twins tended to have similar combinations of pathologies. We
looked not just at the hallmark indicators of Alzheimer's, but at all
the other damage in the brain. Across the whole array of
neuropathological changes, the identical twins appeared to have more
similar pathologies," Gatz said.



"This is fascinating: it's not just a key pathology related to the
twins' diagnoses but the combination of things happening in their
brains. We're going to keep looking for what these combinations are."



Provided by University of Southern California





"Twin brains afflicted with Alzheimer's show similar patterns of neuropathologic changes." February 27th, 2014. http://medicalxpress.com/news/2014-02-twin-brains-afflicted-alzheimer-similar.html
 


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